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Overview
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Specificity: Fusion protein of a Fc fragment (human IgG1 isotype) and the extracellular domain of CTLA-4
Purification method: This fusion protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Endotoxin: <1EU/mg Determined by LAL gel clotting assayPlease contact us at for specific academic pricing.
Background
Recombinant protein composed of the extracellular domain of CTLA-4 fused with the Fc region of human immunoglobulin gamma 1 (hIgG1). Abatacept binds to CD80 (B7-1) with more avidity than to CD86 (B7-2).
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