5-hydroxytryptamine (Serotonin) Receptor 1D - ExpressMAX™ Human GPCR ORF Clones

- Overview
  - GPCR for serotonin, found in nociceptors throughout the body. The anti-migraine action of “triptan” Drugs involves the activation of serotonin subtype 1D (HT1D) Receptors expressed on “pain-responsive” trigeminal primary afferents. HT1D Receptors are present in a similar subpopulation of trigeminal and dorsal root ganglia neurons and in the central terminals of primary afferents.
    
    Includes:
    ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
    – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
    Mammalian Transfection Kits (Cat. No. – PLUS)
    – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
    – 0. 2 mL CANFAST™ Transfection Reagent.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Human GPCR ORF Clones
    
    Other Properties
    
    Plasmid size: 7129 pb
    Promoter: PEF1α
    ORF Sequence (GenBank based): NM_012852
    Protein Sequence (SwissProt): P28565
    Bacterial Selection Antibiotics: Ampicillin
    Mammalian Selection Antibiotic: Neomycin
    Alternative names: 5HT1D
    
    Storage
    
    ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).
    
    * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.
- Applications
  - Application Description
    
    Functional assays, as protein immobilization, cellular localization and other functional assays.
    High-throughput and large scale protein production and purification.
    Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

Documents

Brochure

5-hydroxytryptamine (Serotonin) Receptor 1D - ExpressMAX™ Human GPCR ORF Clones

5-hydroxytryptamine (Serotonin) Receptor 1D - ExpressMAX™ Human GPCR ORF Clones

Documents

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