40 nm Hydroxylated Red Fluorescent Nanodiamond Suspension, zeta potential +25mV, ~1 ppm NV

40 nm Hydroxylated Red Fluorescent Nanodiamond Suspension, zeta potential +25mV, ~1 ppm NV

Catalog Number:
N002336335ADÁ
Mfr. No.:
NDNV40nmHiOH2mL
Price:
$549
  • Size:
    2 mL
    Quantity:
    Add to Cart:
      • Overview
        • Fluorescent nanodiamonds are a chemically robust, infinitely photostable, and biocompatible fluorophore with a range of functional surface chemistries. Relevant applications include fiducial marking, super-resolution microscopy, multiphoton microscopy, time-gated microscopy, and correlative microscopy.

          We offer nitrogen-vacancy (NV) nanodiamonds centers with red-to-near-infrared fluorescence with a variety of surface functionalities. Negatively charged nitrogen-vacancy (NV-) centers possess an electron spin with unique magneto-optical properties: the spin state can be detected optically via optically detected magnetic resonance (ODMR). In turn, the spin state is highly sensitive to the surrounding environment so that changes in the environment can be detected via changes in nitrogen-vacancy (NV) fluorescence. Based on these properties, our customers develop nanodiamond-based quantum sensors of magnetic fields, electric currents, temperature, free radicals, and other phenomena.

          Please contact us at for specific academic pricing.

          Background

          Nanodiamonds (NDs) have been successfully applied in different materials science fields due to their stiffness, lubricity, mechanical resistance, and refractivity. Moreover, due to their high biocompatibility, inherent inertness, ability to easily penetrate cell membranes, and well-established surface chemistry, NDs are explored as a powerful carrier for delivering different drugs within target cells and monitoring intracellular processes.
          The bioconjugation of NDs to specific biomolecules such as peptides, proteins, nucleic acids, and other bioactive molecules can be classified as noncovalent, covalent, and interlayer mediated approaches based on the interactions between NDs and these biomolecules. NDs are able to form complexes with proteins or lipophilic drugs through hydrophobic interactions, while the surface charge of NDs enables the loading of the biomolecules through electrostatic attraction. Since the non-covalent bond interaction is weak and non-specific, biomolecules could gradually detach from the ND surface under biological conditions. For NDs with functional groups such as hydroxyl and carboxyl groups, it is possible to conjugate to biomolecules through covalent bonds, such as ester and amide bonds, thus providing a stronger and more stable connection. To enable practical applications of functionalized NDs in physiological environments, interlayers consisting of hydrophilic polymers are introduced between NDs and bioactive substances to enhance their aqueous dispersibility and provide more functionalities for chemical binding. PEG chains terminated with functional groups such as amino, thiol and azido groups are often employed to selectively bind a range of biomolecules through covalent bonds.

          More Details

      • Properties
        • Categories
          Hydroxylated Red Fluorescent Nanodiamond
          Other Properties
          NV Content: ~1 ppm NV
          Particle Size
          40-50 nm

          * For reaserch use only

      • Applications
        • Application
          microscopy; sensing

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