Name: 4-Fluoro-thalidomide
Price: 129.00 USD

- Overview
  - 4-Fluoro-thalidomide is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966).
    
    Please contact us at for specific academic pricing.
- Properties
  - Alternative Name
    
    835616-60-9 | 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione | Thalidomide 4-fluoride | E3 ligase Ligand 4 | 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione | Thalidomide fluoride | 4-Fluoro-thalidomide | TC E3 5032 | 1H-Isoindole-1,3(2H)-dione, 2-(
    
    CAS Number
    
    835616-60-9
    
    Molecular Formula
    
    C13H9FN2O4
    
    Molecular Weight
    
    276.22
    
    Purity
    
    98%
    
    Other Properties
    
    Solubility: Solubility in Water, DMF, DCM, DMSO
    Boil Point (°C): 520.9±45.0 °C (Predicted)
    Melt Point (°C): 254-256°C
    
    Storage
    
    Store at -20°C
    
    Shipping
    
    Dry ice
    
    SMILES
    
    C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)F
    
    InChi
    
    InChI=1S/C13H9FN2O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5H2,(H,15,17,18)
    
    InChi Key
    
    CRAUTELYXAAAPW-UHFFFAOYSA-N
    
    PubChem CID
    
    11859051
    
    Others
    
    IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindole-1,3-dione
    
    Hazard Information
    
    Signal: Warning
    Hazard Statements: H315,H319,H335,H302,H312,H332,H361
    Precautionary Statements: P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P203,P264+P265,P301+P317,P318,P317,P337+P317,P332+P317,P319
    
    * For research use only. Not for use in human or animal.

4-Fluoro-thalidomide

4-Fluoro-thalidomide

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