4-Chlorophenylguanidine hydrochloride

- Overview
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    Background
    
    4-Chlorophenylguanidine hydrochloride is a potent and selective inhibitor of urokinase [1].
    Urokinase is a serine protease. Its primary physiological substrate is plasminogen, which is an inactive form of plasmin. Urokinase plays an important role in vascular diseases and cancer.
    4-Chlorophenylguanidine hydrochloride inhibited urokinase and trypsin with Ki value of 6.07 μM and 120 μM, respectively [1].
- Properties
  - Alternative Name
    
    2-(4-chlorophenyl)guanidine;hydrochloride
    
    CAS Number
    
    14279-91-5
    
    Molecular Formula
    
    C7H8ClN3·HCl
    
    Molecular Weight
    
    206.07
    
    Appearance
    
    White crystalline solid
    
    Purity
    
    98.00%
    
    Solubility
    
    Soluble to 100 mM in H2O
    
    Storage
    
    Store at RT
    
    * For Research Use Only