Name: 2-Deoxyadenosine-5-triphosphate trisodium
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- Overview
  - 2-Deoxyadenosine-5-triphosphate or dATP, is a nucleotide used by cells to synthesize DNA molecules. 2-Deoxyadenosine-5-triphosphate is used in molecular biology techniques and assays as a substrate of the enzyme DNA polymerase, e.g. polymerase chain reaction (PCR), DNA sequencing, pyrosequencing reactions. Salt form of 2-deoxyadenosine-5-triphosphate has been used in a newly developed detection system for SARS-CoV-2 that combines bioluminescence in real-time (BART) with reverse-transcriptase loop-mediated amplification (RT-LAMP).
    
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- Properties
  - Alternative Name
    
    dATP
    
    CAS Number
    
    54680-12-5
    
    Molecular Formula
    
    C10H13N5O12P3·3Na
    
    Molecular Weight
    
    557.13 g/mol
    
    MDL Number
    
    MFCD11164415
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - Fei et al (2021). A Novel Approach to the Bioluminescent Detection of the SARS-CoV-2 ORF1ab Gene by Coupling Isothermal RNA Reverse Transcription Amplification with a Digital PCR Approach. International Journal of Molecular Sciences, 22(3):1017.
    Kajiyama et al (2011). Optimization of pyrosequencing reads by superior successive incorporation efficiency of improved 2′-deoxyadenosin5′-triphosphate analogs. Analytical Biochemistry, 416(1):8-17.