1q21 and 1p36 Gene Abnormality Detection Kit

1q21 and 1p36 Gene Abnormality Detection Kit

Catalog Number:
ISH1136140CEL
Mfr. No.:
CF1308
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      • Overview
        • Clinical Significance:
          1. 1Q21 (CKS1B) is the most common genetic abnormality in MM. CKS1B gene amplification leads to up-regulation of cell cycle and thus causes many proliferative diseases.
          2. 1Q21 amplification was often associated with MM infiltration phenotype, with poor prognosis and rapid disease progression.
          3. Deletion of 1P32-36 occurs in 16%MM, which leads to the loss of tumor suppressor genes and the occurrence of proliferative diseases
          4. This probe can detect 1P deletion and 1Q21 regional amplification.

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      • Properties
        • Categories
          FISH
          Other Properties
          Probe: 1q21/1p36

          * For research use only.

      • Applications
        • Application
          Fluorescent In Situ Hybridization

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