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Overview
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Calculated MW: 67 kDa
Observed MW: Refer to figures
Gene Accession: NP060445Please contact us at for specific academic pricing.
Background
This protein is essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability.
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