VAMP2 Mouse Monoclonal Antibody

VAMP2 Mouse Monoclonal Antibody

Catalog Number:
A001453613ZEN
Mfr. No.:
Zen-222814
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      • Overview
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          Background

          The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human; rat; mouse; monkey
          Immunogen
          Purified recombinant fragment of human VAMP2 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:6844; UniProt:P63027)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          IHC-P; FC; ELISA
        • Application Dilutions
          IHC 1/100-1/200
          FC 1/50-1/100
          ELISA 1/10000

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