Name: USP12 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 43 kDa
  Observed MW: Refer to figures
  Gene Accession: BC026072
  
  Please contact us at for specific academic pricing.
  
  Background
  
  The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP12 (ubiquitin specific peptidase 12), also known as UBH1 or USP12L1, is a 370 amino acid protein belonging to the peptidase C19 family and the USP12/USP46 subfamily. Considered a deubiquitinating enzyme, it is suggested that USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have high activity. The gene encoding USP12 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Full length fusion protein
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.6 mg/mL
  
  Antigen
  
  Deubiquitinating enzyme 12, OTTHUMP00000042337, UBH 1, UBH1, Ubiquitin carboxyl terminal hydrolase 12, Ubiquitin carboxyl-terminal hydrolase 12, Ubiquitin hydrolyzing enzyme 1 , Ubiquitin specific peptidase 12, Ubiquitin specific processing protease 12, Ubiquitin specific protease 12 like 1, Ubiquitin thioesterase 12, Ubiquitin thiolesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12, UBP12, USP 12, Usp12, USP12L1 (UniProt:O75317)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:500-1:2000
IHC	1:25-1:100
ELISA	1:5000-1:10000

USP12 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

USP12 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

Background

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