Name: UNC45B Polyclonal Antibody (0.9 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 104/95 kDa
  Observed MW: Refer to figures
  Gene Accession: BC101063
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Fusion protein of human UNC45B
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.9 mg/mL
  
  Antigen
  
  Cardiomyopathy associated 4 , CMYA4 , FLJ38610, MGC119540, MGC119541, OTTHUMP00000163855, Protein unc 45 homolog B, Protein unc-45 homolog B, SMUNC45, Striated muscle UNC45, UN45B, Unc 45 homolog B (C. elegans), Unc 45 homolog B, UNC 45B, UNC-45B, UNC45 , UNC45B (UniProt:Q8IWX7)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:500-1:2000
IHC	1:50-1:300
ELISA	1:5000-1:10000

UNC45B Polyclonal Antibody (0.9 mg/mL) for WB, IHC, ELISA

UNC45B Polyclonal Antibody (0.9 mg/mL) for WB, IHC, ELISA

Background

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