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Overview
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Calculated MW: 23 kDa/270 kDa/571 kDa/573 kDa/575 kDa
Observed MW: 600 kDaPlease contact us at for specific academic pricing.
Background
The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein.
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