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Overview
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UBE2W produced in E. Coli is a single, non-glycosylated polypeptide chain containing 171 amino acids (1-151 a.a.) and having a molecular mass of 19.5kDa. UBE2W is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. UBE2W receives ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2W catalyzes monoubiquitination and 'Lys-11'-linked polyubiquitination. UBE2W is broadly expressed, particularly at highest levels in the testis.
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- Properties
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Overview