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Overview
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Calculated MW: 53 kDa
Observed MW: Refer to figures
Gene Accession: BC004178Please contact us at for specific academic pricing.
Background
This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
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