TBP Polyclonal Antibody (1mg/mL) for WB

TBP Polyclonal Antibody (1mg/mL) for WB

Catalog Number:
A001507731RED
Mfr. No.:
RD240487A
Price:
$253
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      • Overview
        • Calculated MW: 38 kDa
          Observed MW: 38 kDa

          Please contact us at for specific academic pricing.

          Background

          The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP,along with a variety of TBP-associated factors,make up the TFIID,a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner,it helps position RNA polymerase II over the transcription start site of the gene. However,it is estimated that only 10-20% of human promoters have TATA boxes. Therefore,TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody detects human TBP (~40 kDa) and mouse/rat Tbp (~35 kDa).

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic peptide of Human TATA-box-binding protein
          Purification
          Antigen Affinity Purification
          Formulation
          PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          GTF2D, GTF2D1, HDL4, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TBP, TFIID, Transcription initiation factor TFIID TBP subunit (Gene ID:6908; UniProt:P20226)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:4000-1:6000

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