SUMO Conjugating Enzyme UBC9 (1D6) Mouse Monoclonal Antibody

SUMO Conjugating Enzyme UBC9 (1D6) Mouse Monoclonal Antibody

Catalog Number:
A001453138ZEN
Mfr. No.:
Zen-220629
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          The process of SUMO-1 conjugation is similar to that seen with ubiquitin and other forms of post-translational protein modification. Like ubiquitin, SUMO-1 is conjugated to its target protein by the coordinated action of ubiquitin conjugation enzymes E1, E2 and E3. Ubc9 (or ube2M) is a highly conserved, 158 amino acid protein that acts as a SUMO-1 conjugating enzyme. Ubc9 binds to target proteins through their SUMO-1-CS (consensus sequence) domains and interacts with SUMO via the structurally conserved amino-terminal domain.

      • Properties
        • Host
          mouse
          Isotype
          IgG1
          Reactivity
          human; monkey
          Clone
          1D6-D9-E7
          Immunogen
          Purified recombinant fragment of human UBE2I expressed in E. Coli.
          Purification
          Ascitic Fluid
          Conjugate
          Unconjugated
          Formulation
          Ascitic fluid containing 0.03% sodium azide.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 18 kDa; Observed MW: 18 kDa
          Antigen
          (Gene ID:7329; UniProt:P63279)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P; ICC/IF; FC
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/100-1/200
          IF 1/50-1/200
          FC 1/50-1/100

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