Stratifin Recombinant Protein

Stratifin Recombinant Protein

Catalog Number:
P001415889ABE
Mfr. No.:
Abe32-3118
Price:
  • Size:
    25 µg
    Quantity:
    Add to Cart:
      • Overview
        • Stratifin Human Recombinant produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 248 amino acids (1-248) and having a molecular mass of 27.7 kDa. Stratifin is purified by proprietary chromatographic techniques. Stratifin is part of the 14-3-3 family. The 14-3-3 family of proteins plays an important regulatory function in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are 7 isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. Stratifin is an epithelial cell marker that functions as a tumor suppressor whose expression can be down regulated via methylation. Failure of Stratifin expression results in a defective G2/M phase checkpoint and results in epithelial and non-epithelial tumorigenesis.

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      • Properties
        • Protein Name
          14-3-3 protein sigma, Epithelial cell marker protein 1, HME1, Stratifin, YWHAS, SFN, Stratifin.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 95.0% as determined by SDS-PAGE.
          Formulation
          Stratifin solution containing 20mM Tris-HCl pH-8, 50mM NaCl and 10% Glycerol.
          Storage
          Stratifin Human Recombinant although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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