STAT6 Mouse Monoclonal Antibody

STAT6 Mouse Monoclonal Antibody

Catalog Number:
A001452877ZEN
Mfr. No.:
Zen-222754
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      • Overview
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          Background

          STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human; mouse; rat; monkey
          Immunogen
          Purified recombinant fragment of human STAT6 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Ascitic fluid containing 0.03% sodium azide.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 94 kDa
          Antigen
          (Gene ID:6778; UniProt:P42226)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; ICC/IF
        • Application Dilutions
          WB 1/500-1/1000
          IF 1/50-1/200

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