SNCA Polyclonal Antibody (1 mg/mL) for WB, IHC-P, ELISA

SNCA Polyclonal Antibody (1 mg/mL) for WB, IHC-P, ELISA

Catalog Number:
A001507668RED
Mfr. No.:
RD236111A
Price:
$253
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      • Overview
        • Calculated MW: 14 kDa
          Observed MW: 15 kDa

          Please contact us at for specific academic pricing.

          Background

          Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthesized peptide derived from the Internal region of human Synuclein-α.
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol pH 7.4.
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          Alpha synuclein, Alpha-synuclein, Alpha-synuclein, isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid, Non A4 component of amyloid precursor, Non-A beta component of AD amyloid, Non-A-beta component of alzheimers disease amyloid, precursor of, Non-A4 component of amyloid precursor, Non-A4 component of amyloid, precursor of, OTTHUMP00000218549, OTTHUMP00000218551, OTTHUMP00000218552, OTTHUMP00000218553, OTTHUMP00000218554, PARK 1, PARK 4, PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4, Parkinson disease familial 1, SNCA, Snca synuclein, alpha (non A4 component of amyloid precursor), SYN, Synuclein alpha, Synuclein alpha 140, Synuclein, alpha (non A4 component of amyloid precursor), SYUA (UniProt:P37840)

          * For reference only.

      • Applications
        • Application
          WB; IHC-P; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:100-1:300
          ELISA 1:10000

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