Small Nuclear RNA Activating Complex, Polypeptide 1

Small Nuclear RNA Activating Complex, Polypeptide 1

Catalog Number:
P001414097ABE
Mfr. No.:
Abe32-4876
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • SNAPC1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 391 amino acids (1-368 a.a) and having a molecular mass of 45.4kDa. SNAPC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Small Nuclear RNA Activating Complex, Polypeptide 1 (SNAPC1) is a part of the SNAPc complex necessary for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC1 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Moreover, SNAPC1 recruits TBP and BRF2 to the U6 snRNA TATA box.

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      • Properties
        • Protein Name
          PTFgamma, SNAP43, snRNA-activating protein complexsubunit 1, SNAPc subunit 1, Proximal sequence element-binding transcriptionfactor subunit gamma, PSE-binding factor subunit gamma, PTF subunit gamma, Smallnuclear RNA-activating complex polypeptide
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 80.0% as determined by SDS-PAGE.
          Formulation
          SNAPC1 protein solution (1mg/ml) contains 20mM Tris-HCl (pH 8.0) and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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