SLC4A4 Rabbit Polyclonal Antibody

SLC4A4 Rabbit Polyclonal Antibody

Catalog Number:
A001453203ZEN
Mfr. No.:
Zen-121226
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
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          Background

          This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogenic process with an apparent stoichiometry of 3 bicarbonate ions per sodium ion. Sodium bicarbonate cotransport is involved in bicarbonate secretion/absorption and intracellular pH regulation. Romero and Boron (1999) reviewed NBCs. Soleimani and Burnham (2000) reviewed NBCs and their regulation in physiologic and pathophysiologic states.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human SLC4A4
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:8671; UniProt:Q9Y6R1)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          IHC-P
        • Application Dilutions
          IHC 1/50-1/100

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