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Sialyl Lewis X pentaose

Sialyl Lewis X pentaose

Catalog Number:
C003137900BIO
Mfr. No.:
OS09845
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      • Overview

        • The blood group antigen Sialyl Lewis X (SLeX) is an oligosaccharide which plays a vital role in cell-cell recognition processes. SLeX is a terminal residue on glycolipids that are present on the surface of white blood cells and plays a key role in inflamation processes (Collins, 2006). The inital adhesion of white blood cells to a site of injury is mediated by E-selectins which specifically interact with SLeX. Cell-cell recognition between leukocytes and endothelial cells in blood is believed to occur in part through interactions between lectins and oligosaccharide ligands (Munro, 1992).

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      • Properties
        • Categories
          Blood Groups and Lewis Antigens
          Alternative Name
          Neu5Ac-a-2-3-Gal-b-1-4(Fuc-a-1-3)GlcNAc-b-1-3-Gal
          Molecular Formula
          C37H61N2O28Na
          Molecular Weight
          1,004.87 g/mol
          MDL Number
          MFCD15145470
          Note
          There is no hazardous surcharge associated with this product.
          There is no special packaging charge associated with this product.

          * For research use only. Not for human or veterinary use

      • Reference

        • Collins (2006) Dictionary of Carbohydrates, Chapman&Hall, S-38, p 873.
          Munro et al (1992) Expression of sialyl-Lewis X, an E-selectin ligand, in inflammation, immune processes, and lymphoid tissues. The American journal of pathology, 141(6).

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