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Overview
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Calculated MW: 25kDa/27kDa/32kDa/36kDa/41kDa
Observed MW: 41kDaPlease contact us at for specific academic pricing.
Background
The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis.
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