SERCA1 ATPase Mouse Monoclonal Antibody

SERCA1 ATPase Mouse Monoclonal Antibody

Catalog Number:
A001452906ZEN
Mfr. No.:
Zen-222726
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      • Overview
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          Background

          This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human; mouse; monkey
          Immunogen
          Purified recombinant fragment of human ATP2A1 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 110 kDa;Observed MW: 110 kDa
          Antigen
          (Gene ID:487; UniProt:O14983)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; FC; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          FC 1/50-1/100
          ELISA 1/10000

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