S100A1 Polyclonal Antibody

S100A1 Polyclonal Antibody

Catalog Number:
A001507659RED
Mfr. No.:
RD232841A
Price:
$253
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      • Overview
        • Calculated MW: 11 kDa
          Observed MW: 10 kDa

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          Background

          The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthesized peptide derived from the N-terminal region of human S-100 α
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          Bpb, NEF, Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 beta, S100 calcium binding protein A1, S100 calcium binding protein B, S100 calcium-binding protein A1, S100 protein alpha polypeptide, S100A, s100a1, S100B, S100beta, S10A1 (UniProt:P23297)

          * For reference only.

      • Applications
        • Application
          WB; IHC-P; IF; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:100-1:300
          IF 1:200-1:1000
          ELISA 1:20000

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