RS 127445 hydrochloride

RS 127445 hydrochloride

Catalog Number:
L002234450BIO
Mfr. No.:
BR165563
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      • Properties
        • Categories
          Ligands of GPCRs
          CAS Number
          199864-86-3
          Molecular Formula
          C17H16FN3·HCl
          Molecular Weight
          317.79 g/mol
          MDL Number
          MFCD11112196
          Note
          There is a hazardous surcharge associated with this product.
          There is no special packaging charge associated with this product.

          * For research use only. Not for human or veterinary use

      • Reference
        • Bonhaus et al (1999). RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist. British Journal of Pharmacology. 127(5):1075-82.
          Bassil et al (2009). Inhibition of colonic motility and defecation by RS-127445 suggests an involvement of the 5-HT2B receptor in rodent large bowel physiology. British Journal of Pharmacology. 158(1):252-8.
          Ohashi-Doi et al (2010). A selective, high affinity 5-HT 2B receptor antagonist inhibits visceral hypersensitivity in rats. Neurogastroenterology & Motility. 22(2):e69-76.

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