RRAGA Polyclonal Antibody (1 mg/mL) for IF

RRAGA Polyclonal Antibody (1 mg/mL) for IF

Catalog Number:
A001509993RED
Mfr. No.:
RD267911A
Price:
$347
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      • Overview
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          Background

          Ras-related GTP-binding protein Ais aproteinthat in humans is encoded by theRRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human RRAGA (NP_006561.1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          RRAGA, FIP-1, FIP1, RAGA (Gene ID:10670; UniProt:Q7L523)

          * For reference only.

      • Applications
        • Application
          IF
        • Application Dilutions
          IF 1:50-1:100

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