RNA Polymerase II Subunit B1 Mouse Monoclonal Antibody

RNA Polymerase II Subunit B1 Mouse Monoclonal Antibody

Catalog Number:
A001452641ZEN
Mfr. No.:
Zen-222646
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      • Overview
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          Background

          This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG2b
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human POLR2A expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:5430; UniProt:P24928)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          FC; ELISA
        • Application Dilutions
          FC 1/50-1/100
          ELISA 1/10000

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