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Overview
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Calculated MW: 57 kDa
Observed MW: 57 kDaPlease contact us at for specific academic pricing.
Background
Prohibitin,also known as PHB,a member of the Band-7 family of proteins,is widely distributed in bacteria,plants,yeast,protozoa and mammals and is important in cell proliferation,differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria,where it acts as a chaperone protein,and is also found in the nucleus,where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB,which is a nuclear matrix protein,affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .
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- Properties
- Applications
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Overview