Recombinant Prohibitin Monoclonal Antibody

Recombinant Prohibitin Monoclonal Antibody

Catalog Number:
A001511503RED
Mfr. No.:
RD87074A
Price:
$392
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      • Overview
        • Calculated MW: 57 kDa
          Observed MW: 57 kDa

          Please contact us at for specific academic pricing.

          Background

          Prohibitin,also known as PHB,a member of the Band-7 family of proteins,is widely distributed in bacteria,plants,yeast,protozoa and mammals and is important in cell proliferation,differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria,where it acts as a chaperone protein,and is also found in the nucleus,where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB,which is a nuclear matrix protein,affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; rat
          Immunogen
          A synthetic peptide of human Prohibitin
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          300 μg/mL
          Antigen
          Epididymis luminal protein 215, Epididymis secretory sperm binding protein Li 54e, HEL 215, HEL S 54e, PHB, PHB, PHB1, Prohibitin (Gene ID:5245; UniProt:P35232)

          * For reference only.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1:500-1:1000
          IHC 1:50-1:100

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