Recombinant PRMT7 Monoclonal Antibody

Recombinant PRMT7 Monoclonal Antibody

Catalog Number:
A001512075RED
Mfr. No.:
RD87073A
Price:
$392
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      • Overview
        • Calculated MW: 30 kDa
          Observed MW: 30 kDa

          Please contact us at for specific academic pricing.

          Background

          Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          A synthetic peptide of human PRMT7
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          300 μg/mL
          Antigen
          [Myelin basic protein]-arginine N-methyltransferase PRMT7, ANM7, FLJ10640, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Myelin basic protein arginine N methyltransferase, OTTHUMP00000174863, PRMT7, Protein arginine methyltransferase 7, Protein arginine N-methyltransferase 7 (Gene ID:54496; UniProt:Q9NVM4)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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