Recombinant Mouse ST6GALNAC2 (C-6His)

Recombinant Mouse ST6GALNAC2 (C-6His)

Catalog Number:
P001411188ABE
Mfr. No.:
Abe32-7829
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      • Overview
        • MW : 40.4kD. Recombinant Mouse Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase 2 is produced by our Mammalian expression system and the target gene encoding Ser28-Arg373 is expressed with a 6His tag at the C-terminus. Alpha-N-acetylgalactosaminide alpha -2,6-sialyltransferase 2, is a type II membrane protein localized in the Golgi network and catalyzes 2,6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis. it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.

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      • Properties
        • Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 50mMTris, 150mMNaCl, pH7.5.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          20446

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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