Recombinant Mouse Interleukin-2/IL­2

Recombinant Mouse Interleukin-2/IL­2

Catalog Number:
P001411390ABE
Mfr. No.:
Abe32-9497
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      • Overview
        • Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma delta T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells. Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity.

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      • Properties
        • Protein Name
          aldesleukin, interleukin 2, interleukin-2, IL-2, IL2, T-cell growth facter, T cell growth factor, TCGF , REF: C1025
          Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Lyophilized from a 0.2 µm filtered solution of 20mM Sodium Citrate, 5% Trehalose, pH4.5.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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