Recombinant LC3A Monoclonal Antibody

Recombinant LC3A Monoclonal Antibody

Catalog Number:
A001512066RED
Mfr. No.:
RD87051A
Price:
$392
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      • Overview
        • Calculated MW: 85kDa
          Observed MW: 85kDa

          Please contact us at for specific academic pricing.

          Background

          LC3,also known as microtubule-associated protein 1 light chain 3 (MAP1LC3),is a mammalian homolog of the yeast Atg8p (autophagy-related 8 protein) that is involved in autophagy process. Three isoforms of LC3 exist as LC3A,LC3B,and LC3C. LC3 is first synthesized as pro-LC3,and undergoes C-terminal cleavage to yield a cytosolic precursor known as LC3-I. During autophagy LC3-I is subsequently conjugated to PE lipid as lipidated form: LC3-II. The lipidated form migrates faster on SDS-PAGE gel. The increased the level of LC3-II has been widely used as autophagy marker. This antibody recognizes both LC3-I and LC3-II.

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          A synthetic peptide of human MAP1LC3A
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          300 μg/mL
          Antigen
          ATG8E, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, LC3, LC3A, MAP1 light chain 3 like protein 1, MAP1 light chain 3-like protein 1, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, MAP1ALC3, MAP1BLC3, Map1lc3a, Microtubule associated proteins 1A/1B light chain 3, Microtubule-associated protein 1 light chain 3 alpha, Microtubule-associated proteins 1A and 1B, light chain 3, Microtubule-associated proteins 1A/1B light chain 3A, MLP3A (Gene ID:84557; UniProt:Q9H492)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:1000

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