Name: Recombinant Lamin A/C Monoclonal Antibody
Price: 392.00 USD

Overview
- Calculated MW: 14kDa
  Observed MW: 16kDa
  
  Please contact us at for specific academic pricing.
  
  Background
  
  The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  A synthetic peptide of human Lamin A/C
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
  
  Storage
  
  Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
  
  Concentration
  
  300 μg/mL
  
  Antigen
  
  70 kDa lamin, Cardiomyopathy dilated 1A (autosomal dominant), CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, Lamin A, Lamin A/C, Lamin A/C like 1, Lamin, Lamin C, Lamin-A/C, LDP1, LFP, LGMD1B, Limb girdle muscular dystrophy 1B (autosomal dominant), LMN 1, LMN A, LMN C, LMN1, LMNA, LMNA, LMNC, LMNL1, Prelamin A/C, PRO1, Renal carcinoma antigen NY REN 32, Renal carcinoma antigen NY-REN-32, Renal carcinoma antigen NYREN32 (Gene ID:4000; UniProt:P02545)
  
  * For reference only.

Applications

Application

WB; IHC-P

Application	Dilutions
WB	1:1000-1:2000
IHC	1:50-1:100

Recombinant Lamin A/C Monoclonal Antibody

Recombinant Lamin A/C Monoclonal Antibody

Background

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