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Recombinant Human Vascular Eendothelial Growth Factor B/VEGFB (N-Fc)

Recombinant Human Vascular Eendothelial Growth Factor B/VEGFB (N-Fc)

Catalog Number:
P001411370ABE
Mfr. No.:
Abe32-9571
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      • Overview

        • VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.

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      • Properties
        • Protein Name
          Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF
          Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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