Name: Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)
Price: Inquiry

- Overview
  - MW : 48.7kD. Recombinant Human Ubiquitin-Conjugating Enzyme E2 K is produced by our E.coli expression system and the target gene encoding Met1-Asn200 is expressed with a GST tag at the N-terminus. Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBE2K is involved in Alzheimers disease, Huntingtons disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Supplied as a 0.2 µm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
    
    Storage
    
    Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    P61086
    
    Gene ID
    
    3093
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)

Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)

More Information

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