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Recombinant Human Type I Inositol 1,4,5-Trisphosphate 5-Phosphatase/INPP5A (C-6His)

Recombinant Human Type I Inositol 1,4,5-Trisphosphate 5-Phosphatase/INPP5A (C-6His)

Catalog Number:
P001412263ABE
Mfr. No.:
Abe32-8429
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      • Overview

        • MW : 48.5kD. Recombinant Human INPP5A is produced by our Mammalian expression system and the target gene encoding Met1-Val410 is expressed with a 6His tag at the C-terminus. Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

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      • Properties
        • Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Q14642
          Gene ID
          3632

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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