Name: Recombinant Human TAR DNA Binding Protein, (1-414 a.a.)
Price: Inquiry

- Overview
  - TARDBP Human Recombinant produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 450 amino acids (1-414 a.a) and having a total molecular mass of 48.8 kDa. TARDBP is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TARDNA Binding Protein (TARDBP) was initially recognized as a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP has been detected in individuals diagnosed with chronic traumatic encephalopathy as well, which is a condition that often imitates ALS and has been related with athletes who have experienced multiple concussions and other types of head injury. TARDBP has been shown to bind both DNA and RNA, it has multiple functions intranscriptional repression, pre-mRNA splicing and translational regulation.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    ALS10, TDP43, TAR DNA-binding protein 43, TDP-43, TARDBP.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 90% as determined by SDS-PAGE.
    
    Formulation
    
    TARDBP protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M urea.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human TAR DNA Binding Protein, (1-414 a.a.)

Recombinant Human TAR DNA Binding Protein, (1-414 a.a.)

We Also Recommend

Recombinant Human Tax1 Binding Protein 3

Recombinant Human TBC1 Domain Family, Member 13

Recombinant Human Tubulin Folding Cofactor A