Recombinant Human Snail Family Zinc Finger 1

Recombinant Human Snail Family Zinc Finger 1

Catalog Number:
P001414089ABE
Mfr. No.:
Abe32-4871
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • SNAI1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 287 amino acids (1-264 a.a) and having a molecular mass of 31.5kDa. SNAI1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Snailhomolog 1 (SNAI1) is involved in induction of the epithelial to mesenchymaltransition (EMT), formation and maintenance of embryonic mesoderm, growtharrest, survival and cell migration. SNAI1 binds to 3 E-boxes of the E-cadheringene promoterand represses its transcription. The nuclear protein encoded by SNAI1 isstructurally identical to the Drosophila snail protein, and is considered aswell to be vital for mesoderm formation in the developing embryo. At least twovariants of a similar processed pseudogene have been found on chromosome 2. Among the diseases associated with SNAI1 are waardenburgsyndrome type iid, and inappropriate adh syndrome.

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      • Properties
        • Protein Name
          Snail Family Zinc Finger 1, ProteinSna, Protein Snail Homolog 1, SNAH, Snail 1 (Drosophila Homolog), Zinc FingerProtein, Snail Homolog 1 (Drosophila), SLUGH2, SNA, SNAIL, SNAIL1, dJ710H13.1, Snail1 Homolog, Snail 1 Zinc Finger Protein, Snail 1, Zi
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greaterthan 85% as determined by SDS-PAGE.
          Formulation
          SNAI1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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