Name: Recombinant Human Protein Phosphatase 1 Regulatory Subunit 14A/PPP1R14A (C-6His)
Price: Inquiry

- Overview
  - MW : 17.76kD. Recombinant Human PPP1R14A is produced by our E.coli expression system and the target gene encoding Met1-Pro147 is expressed with a 6His tag at the C-terminus. Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. In addition, inhibition of PPP1R14A also enhances contraction of smooth muscle in the absence of increment of intracellular Ca2+ concentration.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 0.2mM EDTA, 1mM DTT, 10% Glycerol, pH 8.0.
    
    Storage
    
    Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q96A00
    
    Gene ID
    
    94274
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Protein Phosphatase 1 Regulatory Subunit 14A/PPP1R14A (C-6His)

Recombinant Human Protein Phosphatase 1 Regulatory Subunit 14A/PPP1R14A (C-6His)

More Information

We Also Recommend

Recombinant Human Gankyrin/PSDM10

Recombinant Human Protein Kinase C Type e/PKC e/PKCE (C-6His)

Recombinant Human Protein Phosphatase 1 Regulatory Subunit 1A/PPP1R1A (C-6His)