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Recombinant human PRAME protein with C-terminal human Fc tag

Recombinant human PRAME protein with C-terminal human Fc tag

Catalog Number:
P001417674ABE
Mfr. No.:
Abe32-17352
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      • Overview

        • The protein has a predicted molecular mass of 81.51 kDa after removal of the signal peptide. This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

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      • Properties
        • Protein Name
          CT130; MAPE; OIP-4; OIP4
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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