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Overview
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MW : 40.9kD. Recombinant Human Polyubiquitin-B is produced by our E.coli expression system and the target gene encoding Met153-Gly228 is expressed with a GST, 6His tag at the N-terminus. Polyubiquitin-B(UBB) is one of Ubiquitins. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation.
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Overview