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Overview
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POLE3 Human Recombinant produced in E. coli is a single polypeptide chain containing 170 amino acids (1-147) and having a molecular mass of 19kDa. POLE3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Polymerase (DNA Directed), Epsilon 3, also know as POLE3, is a histone-fold protein which interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers merge into larger enzymatic complexes for DNA transcription, replication, and packaging.
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Overview