Name: Recombinant Human Parathyroid Hormone 1 Receptor/PTH1R (Gly49, C-6His)
Price: Inquiry

- Overview
  - MW : 20.2kD. Recombinant Human Parathyroid hormone 1 receptor is produced by our Mammalian expression system and the target gene encoding Tyr23-Met189 is expressed with a 6His tag at the C-terminus. Parathyroid hormone 1 receptor(PTH1R) is a multi-pass membrane protein. The protein is expressed in high levels in bone and kidney and regulates calcium ionhomeostasis through activation of adenylate cyclase and phospholipase C. In bone, it is expressed on the surface of osteoblasts. When the receptor is activated through PTH binding, osteoblasts express RANKL (Receptor Activator of Nuclear Factor kB Ligand), which binds to RANK (Receptor Activator of Nuclear Factor kB) on osteoclasts. This turns on osteoclasts to ultimately increase the resorption rate.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q0VGD7
    
    Gene ID
    
    5745
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Recombinant Human Parathyroid Hormone 1 Receptor/PTH1R (Gly49, C-6His)

Recombinant Human Parathyroid Hormone 1 Receptor/PTH1R (Gly49, C-6His)

More Information

We Also Recommend

Recombinant Human Roundabout Homolog 4/ROBO4 (C-Fc)

Recombinant Human SLAM Family Member 8/BLAME/SLAMF8/BLAME (C-6His)

Recombinant Mouse Fc gamma RII/CD32b/FCGR2 (C-6His)