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Overview
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MW : 48.92kD. Recombinant Human Nucleolar Protein 3 is produced by our E.coli expression system and the target gene encoding Met1-Ser208 is expressed with a GST tag at the N-terminus. Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in RNA splicing. Isoform 2 may inhibit apoptosis. It has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53.
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Overview