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Recombinant Human Neutrophil Cytosolic Factor 1

Recombinant Human Neutrophil Cytosolic Factor 1

Catalog Number:
P001413538ABE
Mfr. No.:
Abe32-4293
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  • Size:
    10 µg
    Quantity:
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      • Overview

        • NCF1 Recombinant Human produced in E. Coli is a single, non-glycosylated polypeptide chain containing 398 amino acids (1-390 a.a.) and having a molecular mass of 45.7 kDa. The NCF1 is fused to an 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques. NCF1 is a cytosolic subunit protein of neutrophil NADPH oxidase which aMulti-component enzyme that is activates production of superoxide anion. NCF1, along with NCF2 and a membrane bound cytochrome b558, is necessary for activation of the latent NADPH oxidase necessary for superoxide production. Mutations in this NCF1 have been related with chronic granulomatous disease.

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      • Properties
        • Protein Name
          NCF1A, NOXO2, p47phox, SH3PXD1A .
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90.0% as determined by SDS-PAGE.
          Formulation
          0.5mg/ml solution containing 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl & 20% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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