Name: Recombinant Human Neuronal Acetylcholine Receptor Subunit beta-3/CHRNB3 (C-6His)
Price: Inquiry

- Overview
  - MW : 25.3kD. Recombinant Human CHRNB3 is produced by our Mammalian expression system and the target gene encoding Ile25-Leu232 is expressed with a 6His tag at the C-terminus. Neuronal acetylcholine receptor subunit beta-3(CHRNB3) is a cell membrane protein and belongs to the ligand-gated ion channel (TC 1. A.9) family. CHRNB3 seems to be composed of two different type of subunits: alpha and beta. The CHRNB3 are (hetero) pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of CHRNB3 are encoded by separate genes and have different primary structure. There are several subtypes of neuronal CHRNB3 that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if like muscle alpha-1, they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits.
    
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- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q05901
    
    Gene ID
    
    1142
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Neuronal Acetylcholine Receptor Subunit beta-3/CHRNB3 (C-6His)

Recombinant Human Neuronal Acetylcholine Receptor Subunit beta-3/CHRNB3 (C-6His)

More Information

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