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Overview
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MX1 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 685 amino acids (1-662 a.a) andhaving a molecular mass of 77.9kDa. MX1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Myxovirus Resistance 1, also known as MX1 is a guanosine triphosphate(GTP)-metabolizing protein which takes part in the cellular antiviral response. MX1 is induced by type I and type II interferons, and also antagonizes thereplication process of some different RNA & DNA viruses. In addition, thereis a related gene located adjacent to MX1 on chromosome 21, and there aremultiple pseudogenes positioned in a cluster on chromosome 4.
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Overview