Recombinant Human Mitochondrial Ribosomal Protein L48

Recombinant Human Mitochondrial Ribosomal Protein L48

Catalog Number:
P001413496ABE
Mfr. No.:
Abe32-4242
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • MRPL48 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 207 amino acids (29-212 a.a) andhaving a molecular mass of 23.1kDa. MRPL48 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Mitochondrial Ribosomal Protein L48, also known as MRPL48, is amammalian mitochondrial ribosomal protein which assists in protein synthesiswithin the mitochondrion. Mitochondrial ribosomes, mitoribosomes, consist of asmall 28S subunit and a large 39S subunit. They include an estimated 75%protein to rRNA composition while comparing to prokaryotic ribosomes, wherethis ratio is reversed. An additional dissimilarity between mammalian mitoribosomes & prokaryoticribosomes is that the latter contain a 5S rRNA. Between different species, theproteins containing the mitoribosome differ very much in sequence, as well as inbiochemical properties from time to time, which prevents easy recognition throughsequence homology. MRPL48 encodes a 39S subunit protein. A pseudogenecorresponding to MRPL48 is found on chromosome 6p.

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      • Properties
        • Protein Name
          Mitochondrial Ribosomal Protein L48, MRP-L48, L48MT, 39SRibosomal Protein L48, Mitochondrial, CGI-118, HSPC290, 39S ribosomal proteinL48, mitochondrial.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85% as determined by SDS-PAGE.
          Formulation
          MRPL48 protein solution (1 mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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