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Recombinant Human Methionine Aminopeptidase 1D/MetAP1D/MAP1D (N, C-6His)

Recombinant Human Methionine Aminopeptidase 1D/MetAP1D/MAP1D (N, C-6His)

Catalog Number:
P001410954ABE
Mfr. No.:
Abe32-8122
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      • Overview

        • MW : 35.4kD. Recombinant Human MetAP1D is produced by our E.coli expression system and the target gene encoding Arg44-Ala335 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus. Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 50mM Tris, 100mM NaCl, pH 8.0.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Q6UB28
          Gene ID
          254042

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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